کلیات ایمنی درمانی سرطان

عنوان فارسی:          ایمنولوژی سرطان: ایمنوتراپی سرطان از صندلی تا بالین

عنوان انگلیسی:      Cancer Immunology: Bench to Bedside Immunotherapy of Cancers

This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for targeting tumor immunosuppression, gene therapy, virus-based vaccines, targeting of cancer stem cells, hematopoietic stem cell transplantation, the role of T lymphocytes in cancer immunotherapy, use of monoclonal antibodies, and many more innovative approaches. Clinical immunologists, hematologists, and oncologists in particular will find the book to be of value in expanding their knowledge. The book is the second in a three-volume series, Cancer Immunology, which offers an up-to-date review of cancer immunology and immunotherapy. The remaining volumes focus on the immunopathology of cancers and cancer immunotherapy for organ-specific tumors. In total the series, designed for both clinicians and researchers, includes contributions from more than 250 scientists working at leading universities and institutes from across the world.

• Offers an up-to-date review of cancer immunology in animal models and human cancers
• Provides a bench to bedside approach to the immunology of cancers, with a focus on clinical aspects
• Describes in depth the interactions between cancerous cells and various components of the innate and adaptive immune system

1. Frontiers in Cancer Immunotherapy
2. Novel Strategy of Cancer Immunotherapy: Spiraling Up
3. Novel Prognostic Biomarkers for Personalized Cancer Treatment
4. Tumor Antigen and Epitope Identification for Preclinical and Clinical Evaluation
5. Strategies to Target Tumor Immunosuppression
6. Overcoming Cancer Tolerance with Immune Checkpoint Blockade
7. Gene Therapy and Virus-Based Cancer Vaccines
8. Cancer Stem Cells: Biology and Potential Therapeutic Applications
9. Immunologic Approaches to Targeting Cancer Stem Cells
10. Hematopoietic Stem Cell Transplantation and Lymphodepletion for the Treatment of Cancer
11. Combination of Chemotherapy and Cytokine Therapy in Treatment of Cancers
12. T Cell Immunotherapy: From Synthetic Biology to Clinical Practice
13. Role of γδ T Lymphocytes in Cancer Immunosurveillance and Immunotherapy
14. Adoptive T-Cell Therapy: Optimizing Chemokine Receptor-Mediated Homing of T Cells in Cancer Immunotherapy
15. B Cell Regulation of Antitumor Response
16. Monoclonal Antibodies for Cancer Immunotherapy
17. Toll-Like Receptor Pathway and its Targeting in Treatment of Cancers
18. Recent Advances in the Use of NK Cells Against Cancer
19. Dendritic Cell Vaccines for Cancer Therapy: Fundamentals and Clinical Trials
20. Tumor-Associated Macrophages and Cancer Development
21. Photodynamic Therapy and Antitumor Immune Response
22. Polarization of Tumor Milieu: Therapeutic Implications
23. Immunotherapies Targeting a Tumor-Associated Antigen, 5T4 Oncofetal Glycoprotein
24. Emerging Biomarkers During Clinical Development of Anti-CTLA4 Antibody Therapy
25. New Advances in Radioimmunotherapy for the Treatment of Cancers
26. Psychoneuroendocrinoimmunotherapy of Cancer
27. Ethical Considerations in Cancer Immunotherapy