فناوری ایمنی تشخیصی از آزمایشگاه تا بالین

عنوان فارسی:         فناوری ایمنی تشخیصی از آزمایشگاه تا بالین

عنوان انگلیسی:      Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

• The book comprehensively describes the most recent methods for immunodiagnostics
• It compiles the latest information on the application of immunodiagnosis in the various areas of Biomedicine
• It elucidates the translational potential of various immunodiagnostics
• It gives a detailed overview of the major shortcomings and the proposed troubleshooting of the technology

1. Biosensors for Clinical Samples: Consideration and Approaches
2. Immunodiagnosis by Electrochemical Multiplexing in Clinical Samples
3. Principle and Applications of Immunodiagnostics Using Radioisotope as Tracers
4. Redox Cycling Technologies for Point-of-Care Immunodiagnostics in Various Matrices
5. Next-Generation Immunosensing Technologies Based on Nano-Bio-Engineered Paper Matrices
6. Alternative Analyte-Binding Compounds for Immunosensor-Like Point-of-Care Application
7. Bead-Based SELEX for Aptamers Selection and Their Application in Detection of Diverse Antigens
8. Changing Trends in Immunosensing Technologies and Their Commercial Aspects in Animal Health and Welfare
9. Methods for Enhancing Aptamer Affinity for Antigen Detection and Its Characterization
10. Application of Biosensors to Enhance Reproductive Efficiency and Production of Livestock and Poultry by Diverse Antigen Analysis
11. Clinical Implications of Cortisol and Bioanalytical Methods for Their Determination in Various Biological Matrices
12. Receptors in Immunodiagnostics: Antibodies, Antibody Fragments, Single Domain Antibodies and Aptamers